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Efficacy
Phase III Study Primary Endpoints
Success in ISGA: Clear or almost clear
Study Design
Phase III Study Secondary Endpoints
ISGA clear or almost clear
Time to ISGA success
Phase III Study: Other Endpoints
Pruritus
Quality of life assessments
Infant Study: Exploratory efficacy Endpoints
ISGA clear or almost clear
%BSA, EASI & POEM
Safety Data
Phase III Study Adverse Reactions*
Pivotal trial & 48-week extension study
Adverse Reactions
Open-Label Safety Extension Study*
Open-Label Safety Extension Study Rescue Therapy Endpoint
Study design
Infant Safety Study**
Adverse Reactions
Study design and Demographics
Savings & Support
Events
Materials
Videos
Copay Cards
Cost and Coverage
Pooled results from 2 pivotal studies in patients 2 years and older3
Baseline scores of both the DLQI and the CDLQI in the pivotal trials reflect a moderate effect of atopic dermatitis on patient lives.4-6
Composite scores are based on a scale of 0-304-6
The higher the score, the greater the impairment of QoL.7
MCID (or MID, as it is sometimes referred to) is the smallest difference in score that suggests there has actually been a meaningful change in studied patients’ quality of life since the previous measurement of his/her scores that would lead the patient or clinician to consider a change in management.8,9
CDLQI is validated for use in children 4-16 years of age and can be completed with the help of the child's parent or guardian. The data presented includes patients 2-15 years of age. These results are consistent with the findings of a sub-group analysis in patients 4-15 years of age.6
Find out more about the proportion of patients aged 2 years and older who achieved ISGA clear or almost clear at day 29 from the Phase III trial's secondary endpoint
** This is an optional area where footnotes can live.
Hear JP with mild-to-moderate AD explain what EUCRISA means to him and other babies like him
Not an actual patient
Learn more about 28-day, open-label, single-arm, safety study in 3 to <24 month old patients14
** This is an optional area where footnotes can live.
Find out more about the proportion of patients who achieved clear or almost clear at day 29 in the primary endpoint
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The specific mechanism(s) of action of crisaborole in atopic dermatitis is not well defined. PDE4=phosphodiesterase 4
*Eligible patients pay as little as $10
Terms and Conditions apply
* Patients enrolled in state or federally funded prescription insurance programs are not eligible to use this card. Savings up to $970 per tube. Annual savings up to $3,880. This card will be accepted only at participating pharmacies. This card is not health insurance.
** This is an optional area where footnotes can live.
A savings and support program for your patients to help them with their access to EUCRISA
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Register or sign in to check availability and request samples.
** This is an optional area where footnotes can live.
Contraindications
EUCRISA is contraindicated in patients with known hypersensitivity to crisaborole or any component of the formulation.
Warnings and Precautions
Hypersensitivity reactions, including contact urticaria, have occurred in patients treated with EUCRISA and should be suspected in the event of severe pruritus, swelling, and erythema at the application site or at a distant site. Discontinue EUCRISA immediately and initiate appropriate therapy if signs and symptoms of hypersensitivity occur.
Adverse Reactions
The most common treatment-related adverse reaction occurring in clinical trials was application site pain, such as burning or stinging.
Please see Full Prescribing Information and Patient Information
EUCRISA is indicated for topical treatment of mild-to-moderate atopic dermatitis in adult and pediatric patients 3 months of age and older.
EUCRISA (crisaborole) is indicated for topical treatment of mild‑to‑moderate atopic dermatitis in adult and pediatric patients 3 months of age and older.
EUCRISA is for topical use only and is not for ophthalmic, oral, or intravaginal use. For more information, please view the full prescribing information here.
Please see full Prescribing Information.
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